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In addition, as discussed previously, the alteration in bile acid absorption may result in increased GLP-1 secretion, in a similar way to that observed with bile acid sequestrants such as colesevelam [76, 77]

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The combination of all three receptors firing simultaneously creates what researchers describe as synergistic metabolic effects, meaning the total impact exceeds what you would get from activating each receptor individually

These challenges, intensified by the recent global pandemic, continue to endanger both human and animal health [2]