While the neuroprotective effect in preclinical studies is clear, clinical findings have so far failed to demonstrate an arresting effect on cognitive
Your expectations are too high
Mitochondrial ATP synthesis The conversion of energy from carbohydrates and fats to ATP, the form of energy used by cells, requires the presence of coenzyme Q 10 in the inner mitochondrial membrane
For subjects treated with the highest dose of tirzepatide (15 mg per week), the risk to develop any major adverse cardiovascular event (MACE-4 composed of myocardial infarction, stroke, hospitalization for angina, and all-cause death) was estimated at 050 (026095)
The most common side effects were of a gastrointestinal nature and were in line with the profile known for GLP-1 drugs
Zhou et al., 2013b), simvastatin lactone (Zhao et al., 2017), and lovastatin lactone (Zhao et al., 2017)