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Aging Pathobiol Ther , 2019, 1(1): 5-9
Mechanism of action Reduction of total fluid volume occurs through the inhibition of sodium and chloride reabsorption in the ascending loop of Henle, which causes increased excretion of water, sodium, chloride, magnesium, and calcium
[2] Madzarac, Goran , et al
Ca(2+) homeostasis during mitochondrial fragmentation and perinuclear clustering induced by hFis1
Although 10 days of IH did not cause measurable increases in either proliferation or population size of unlabeled neural precursors, the demonstration that exposure to IH EARLY results in larger proportions of labeled neurons derived from wildtype NSCs supports the perspective IH activates pro-neurogenesis signaling during early stages of adult neurogenesis