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Side Effects: Tirzepatide is a new drug that is now being tested in humans

Consider the cost of treatment Injectable semaglutide is relatively expensive, while the cost of oral semaglutide varies depending on the type and frequency of use

By activating both receptor pathways, tirzepatide achieves reductions in HbA1c levels (typically 1.52.1% [16-23 mmol/mol] from baseline in the SURPASS clinical trials) and weight loss (averaging 5-15% of body weight in type 2 diabetes and 15-20% in obesity at the 10-15mg doses in the SURPASS and SURMOUNT trials)

Understanding the comparative early efficacy of tirzepatide and semaglutide may help clinicians to appropriately set expectations with patients and adjust dose/alter treatments per each patients needs