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2008;47 Suppl 3:4-24

H., Dawson-Hughes, B., Lips, P., Munns, C

549 The reactive astrocytes can promote excitotoxic injury of motor neurons by producing nitric oxide and peroxynitrite, which cause mitochondrial damage and apoptosis in cultured neurons, decreasing glutamate transport, releasing pro-apoptotic mediators selectively toxic to motor neurons

These FDA-approved medications for type 2 diabetes and chronic weight management work by mimicking a natural gut hormone that slows gastric emptying and alters intestinal motility

Regarding protein expression of SOD, MASH patients displayed elevated SOD2 protein levels as compared to control subjects (Shearn et al