Currently, the off-label long-term use of phentermine is indicated only if there is clinical benefit, stable blood pressure and pulse rate in the absence of cardiovascular history or substance abuse disorders
Merinero B, Prez-Cerd C, Font LM, Garcia MJ, Aparicio M, Lorenzo G, et al
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As of now, no drugmaker has an early-stage migraine-specific GLP-1 drug program, according to publicly available information