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The DNA of Gstp knockout mice was extracted and subjected to PCR by using MightyAmp Genotyping Kit (Takara, Ohtsu, Japan), which as shown in Figure S1C in Supplementary Material

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20.4% CagriSema Trial REDEFINE 2 (NEJM 2025) Duration 68 weeks Population T2D + BMI 27 (n=1,206) Mean Weight Loss 13.7% CagriSema vs 3.4% placebo