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Early animal and laboratory studies have explored its potential role in tissue repair and inflammation, but its cardiovascular effects and risks in humans remain unknown

Gene Expression 2018 4,048 Gene Expression Changes Identified Comprehensive analysis of GHK-Cus regenerative and protective actions in light of new gene expression data, demonstrating modulation of pathways for tissue remodeling, antioxidant response, and anti-inflammatory signaling

Because of this, the effects in human patients are unconfirmed

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However, they are not normally considered DME

doi: 10.1016/j.freeradbiomed.2009.10.039 84 Mason-OsannEPomeroyAEPalmerACMettetalJT