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That means hair loss was reported 2.46 times more frequently than the baseline expectation across all medications in the database

GLP-1RAs can suppress local inflammation caused by agonistic anti-CD3 antibody through intraepithelial lymphocytes (IELs) (Wong et al., 2022)

The difference reflects population: TRIUMPH-4's osteoarthritis cohort was older and more comorbid

Combination therapies (GLP-1s with other peptides, metabolic drugs, or lifestyle protocols like the ProLon Fasting Mimicking Diet ) are already being studied to push results even further

Encouraging strength-preserving habits, like resistance-based activity or high-protein diets, can help reduce risk, especially in older adults or patients on long-term treatment plans

Because muscle is metabolically active, maintaining it maximizes the energy-burning effects, making the weight loss more sustainable and impactful