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Weight Loss and Initial Fluid Changes Tirzepatide produces substantial weight lossclinical trials show average reductions of approximately 15% of body weight over 72 weeks in obesity trials (SURMOUNT-1) and somewhat less in type 2 diabetes trials (SURPASS program)

Peptides might be add-ons, not front line treatments

How many human participants were included

I would say

Additionally, a National Library of Medicine report found that adult obesity is associated with average annual increased medical costs of $1,861 per person

Particle size distribution: The polydispersity index (PDI) measures the uniformity of particle sizes