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NNMT inhibition by 5-Amino-1MQ preserves the cellular nicotinamide pool important for NAD+ biosynthesis and conserves the methyl-donor pool by reducing SAM consumption

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This holistic approach can provide insights into how lifestyle modifications can complement antioxidant therapies

Methanol was quantified using GC-FID and kept between 500 and 1,000 mM by constant feeding of pure methanol at manually set rates depending on the growth stage of the culture

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8j) or the activity of mice in the open field test (Supplementary Fig