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Studies show nasal Melanotan has less than 5% bioavailability, making meaningful tanning impossible while still causing systemic side effects 6

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PT-141 results in increased production of nitric oxide (NO) synthesized from neuronal nitric oxide synthase (nNOS), with the NO activating soluble guanylate cyclase to catalyze the conversion of guanosine triphosphate (GTP, also called guanosine 5'-triphosphate) to cGMP

Patients describe being able to stay mentally in their sessions longermore focus, better form, fewer fall-off points where discipline gets replaced by fatigue