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Patients taking certain medications (e.g., chloramphenicol may reduce the effectiveness of B12 therapy) or with risk factors for B12 deficiency (metformin use, proton pump inhibitors, nitrous oxide exposure, vegan diet) should discuss these with their healthcare provider

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Serious side effects such as chest pain, severe allergic reactions, and irregular heartbeat require immediate medical attention

In a bulking phase, the priority is heavy resistance training focused on compound lifts like squats, bench press, deadlifts , and rows