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These impairments significantly impact an individuals ability to carry out daily activities and may result in long-term disability [227, 228]

PMID 3921200

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Inhibition of glycolysis decreases the expression of IL-6, IL-8, IL-1 and COX-2 induced by bTNF- in bFLS We have previously reported that bTNF- increases the expression of glycolytic genes such as GLUT1 and PDK1 24

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