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Polyethylene glycol-like brush polymer conjugate of a protein drug does not induce an antipolymer immune response and has enhanced pharmacokinetics than its polyethylene glycol counterpart

Bacteriostatic water, sterile water, saline, acetic acid water, and buffered solvent systems are not chemically identical

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Conclusions These findings might be related to the intra-erythrocytic chemical alterations seen in thalassemic individuals

Nausea and diarrhea rates are comparable between the two compounds