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The peptide binds G-actin monomers reversibly, regulating the cytoplasmic pool of polymerizable actin and therefore influencing all cellular processes that depend on actin dynamics

Spermidine attenuates bleomycin-induced lung fibrosis by inducing autophagy and inhibiting endoplasmic reticulum stress (ERS)-induced cell death in mice

In general, monocytes and their macrophage and dendritic cell progeny serve three main functions in the immune system

Induction of apoptosis through the PKC pathway in cultured dermal papilla fibroblasts

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IGF-1 DES shows moderately reduced IGFBP affinity, with greater selectivity it particularly reduces affinity for IGFBP-1, IGFBP-2, and IGFBP-4, but retains more binding to IGFBP-3 than IGF-1 LR3 does