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Hemolysis and hemolytic uremic syndrome following five-fold N-acetylcysteine overdose

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Both eliminates free radicals as well as protects cells from the destructive effects of these structures

Interestingly, as tryptophan FI decreased at pH 5, 7, and 9, tyrosine FI increased relative to its low level at pH 3, which indicates spatial separation from tryptophan residues (Jones & Farrens 2014)