However, the recent FDA approvals of Wegovy (2021) and Zebound (2023) for weight loss have been met with a tremendous increase in demand for these drugs
In the study, the average weight loss was about 15% for 5 mg, 19.5% for 10 mg, and 20.9% for 15 mg in adults with obesity or who are overweight without type 2 diabetes
While semaglutide remains highly effective, recent studies compared it to tirzepatide (Mounjaro for diabetes, Zepbound for obesity), a dual GIP/GLP-1 receptor agonist targeting two hormone receptors
Staying Hydrated and Avoiding Nausea Dehydration amplifies nausea on tirzepatide, yet many patients accidentally under-drink because reduced appetite suppresses thirst cues too
While some of these are FDA-registered and inspected, others may operate under inconsistent standards
They also found that prescribing was most common in those with private insurance