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doi: 10.1186/s40779-025-00609-z

The buffering genetic interaction revealed from our CRISPR screen 13 allowed further extending the finding by demonstrating a functional coordination of mitochondrial glutathione uptake (mediated by SLC25A39) and mitochondrial iron import (mediated by SLC25A37) in supporting OXPHOS

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It's unique in that, rather than trying to block dopamine postsynaptically, it regulates, or modulates, the release of dopamine and the ventral tegmental limbic circuits

The final step in the process is proper storage

In this group at six hour intervals, unlike in diazepam conditioned mice, isoniazid preconvulsive latencies were still longer than in corresponding controls