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The most common side effects reported in clinical trials were: Nausea Vomiting Diarrhea Stomach pain Constipation Weight loss Less common but more serious side effects include: Serious, lifethreatening allergic reactions Increased risk of certain thyroid tumors, including medullary thyroid carcinoma (MTC) Increased risk of multiple endocrine neoplasia syndrome type 2 (MEN 2) Pancreatitis (inflammation of the pancreas) Diabetic retinopathy complications and vision changes Low blood sugar (hypoglycemia), especially when used with other diabetes medications Worsening kidney disease Gallbladder disease and gallstones This list is not exhaustive

But if history is any guide, access will expand rather than contract as the evidence base grows and medication costs decrease

Additionally, it has enhanced our understanding of how herbal medicines can work synergistically to address complex conditions like cancer, diabetes, and neurodegenerative diseases by linking multiple biological targets and pathways simultaneously [70]