Papaya enzyme (Papain) is generally much gentler than Alpha Hydroxy Acids (AHAs), making it the ideal brightening choice for those with reactive or sensitive skin
Many peptides show remarkable effects in animal models that do not translate to equivalent human benefits
Acknowledgements The authors thank Emelia Tremblay and Mazie Gordon at the University of Maine, for their help with microbial lab work, Benjamin and Timothy Hunt at the University of Maine for their work reviewing literature on GR converting genes, and Scott Leonard at Oregon State University for analyzing urine samples for nitrile content
Clean wound and apply sterile dressing
MGO is then converted into lactoylglutathione (LGSH) by glyoxalase 1 (GLO1) with the assistance of glutathione [32, 33]
Pulsatile dosing: Some experiment with dose cycling (e.g., one month on, one month off) to minimize tolerance development