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In summary, the GLP-1 receptor remains an interesting and noteworthy target for the pharmacotherapy of central nervous system diseases, not only those related to neurodegeneration and substance abuse, but GLP-1RA drugs may also prove effective as adjunctive therapies in the treatment of mood disorders such as depression

Nonetheless, a decrease in PI3K, Akt, mTOR, proliferation, migration, invasion, p-ERK1/2, growth, colony formation, and inflammation represented by nuclear factor B (NF-B) expression, cell viability, and an overall decrease in proliferation was noted with applying liraglutide (Table 1)

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So this is a potential medication that could produce the weight loss and still preserve bone