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The induction and intensification of cell death, along with barriers to macrophage clearance and absorption of dead cells, increase the exposure of intracellular contents to the immune system, triggering an immune response

Nausea ranged from approximately 11% at the lowest 1 mg dose to 64% in some intermediate-dose arms, with about 33% in the 9 mg fixed-dose (highest-efficacy) arm

Treatment with FOXO4-DRI following chemotherapy exposure potently counteracts these effects, normalizing body weight and reducing plasma AST to near-baseline levels

GLP-1 and GIP/GLP-1 receptor agonists require refrigeration between 36F and 46F (2C to 8C) until first use

Wilson and Olson, 1990)

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