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Although mitochondrial respiration was noted as unchanged in resting and stimulated CD4+ and CD8+ T cells, CD8+ T cells were found to have a reduction in proton leak, ATP synthesis, and mitochondrial membrane potential (254)

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These included: improving the in vivo stability of the GLP-1 analogue peptide which was significantly shorter than the antibody moiety

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Any substance that could theoretically support tumor growth deserves extra caution in this population