Nanovaccines delivering T cell-specific epitopes induce antigen-specific tolerance and significantly lower inflammatory responses in preclinical models (39)
Chronic marginal iron intakes during early development in mice alter brain iron concentrations and behavior despite postnatal iron supplementation
KPV is a tripeptide and the smallest species in the vial at 342.4 g/mol, so it is the component most readily lost to adsorption and to filtration or dialysis steps with a molecular weight cut-off
Tirzepatide increased force of contraction in the isolated human atrium
The authors administered oral Dihexa to APP/PS1 transgenic mice (a standard amyloidopathy model of Alzheimers disease) and showed that brain AngIV levels were elevated relative to wild-type after Dihexa administration, that spatial learning and memory were restored on Morris water maze testing, that hippocampal neuronal density and synaptophysin protein expression were preserved, that astrocyte and microglial activation were reduced, and that pro-inflammatory cytokines (IL-1, TNF-) decreased while anti-inflammatory IL-10 increased
Melatonin protects periventricular white matter from damage due to hypoxia
