In this situation, the stomach is pushed down the oesophagus (protrudes) through the diaphragms opening
This activation enhances glutamate release from primary afferent terminals, resulting in increased normal and miniature excitatory postsynaptic currents, and elevates PKC activity, which mediates the phosphorylation of NMDARs (e.g., the GluN1 subunit at Ser896)
That is the default setting for a man at 50 who changes nothing
Vaduganathan M, Docherty KF, Claggett BL, Jhund PS, de Boer RA, Hernandez AF, Inzucchi SE, Kosiborod MN, Lam CSP, Martinez F, et al
Sonntag, Anna Csiszar, Raphael de Cabo, Luigi Ferrucci, Zoltan Ungvari, Diverse Roles of Growth Hormone and Insulin-Like Growth Factor-1 in Mammalian Aging: Progress and Controversies, The Journals of Gerontology: Series A, Volume 67A, Issue 6, June 2012, Pages 587598, Mario Thevis (13 December 2010)
FEDGOV TODAY June 7, 2026 From Rural Clinics to Remote Recovery: How Telehealth Is Transforming American Healthcare Telehealth has evolved from an emerging technology into a critical component of healthcare delivery, helping providers reach patients wherever they live while improving access to quality care
