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Tola EN, Mungan MT, Uuz AC, Nazirolu M

The review further characterized BPC157s modulation of dopaminergic and serotonergic neurotransmitter systems in the context of central nervous system regulatory biology, proposing mechanistic connections between peripheral peptide signaling and centrally observed neuroprotective and neuroregenerative outcomes

Acknowledgments We express our gratitude to BioRender (www.BioRender.com) for their graphical assistance during the preparation of this manuscript

While the EPSILON study 1-year results of no increase in motor complicationsin particular dyskinesiarates after total exposure over 76 weeks are encouraging, they cannot exclude that such an increase would be seen with prolonged treatment over longer time periods

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