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Serum ferritin levels were found to be significantly lower in FMS patients, perhaps due to the role of iron as a cofactor in enzymes involved in neurotransmitter synthesis

However, the upregulation of glutathione can be a negative factor when it comes to preventing out-of-control cellular growth in cancer.[ref] Low glutathione levels are found in a number of different chronic diseases

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Glutathione synthetase deficiency is the most frequently recognized disorder and, in its severe form, it is associated with hemolytic anemia, metabolic acidosis, 5-oxoprolinuria, central nervous system (CNS) damage and recurrent bacterial infections