Biochemical characterization of a trypanosome enzyme with glutathione-dependent peroxidase activity
Multiple alternatively spliced transcript variants encoding different isoforms have been found.Synonyms: GLUR, GR, GRD1, GRase, GSR Molecular Weight 56257 Da Gene ID 2936 NCBI Accession NP_000628 Pathways Thyroid Hormone Synthesis, Cell RedoxHomeostasis Target
Coffee and caffeine intake and risk of urinary incontinence: a meta-analysis of observational studies
Studies have shown that this antioxidant activity can improve skin brightness (by reducing melanin), increase skin moisture, improve skin elasticity and minimize the appearance of wrinkles, resulting in a more youthful skin, all without significant side effects
Even more intriguing is the notion that GGT-mediated hydrolysis of GSH can create a low level of ROS, due to generation of the more reactive thiol cysteinylglycine, which can reduce ferric iron to ferrous iron and trigger an iron redox cycling with production of ROS (Paolicchi et al., 2002)
Use salicylic acid as toners, cleansers, or spot treatments