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2.3 Acute oral toxicity study Acute oral toxicity study was designed based on the guidelines provided by the Organisation for Economic Co-operation and Development No.423 (OECD 423), Acute Oral Toxicity - Acute Toxic Class Method (OECD, 2002b)

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The FDA-approved injection sites include: abdomen (avoiding a 2-inch radius around the navel), front of thighs, and outer upper arms

Tests in bacteria, cells, and mice all came back negative, suggesting the compound does not pose carcinogenic risk through DNA damage mechanisms