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It involves staged removal with real-time frozen-section histopathology read by the surgeon between stages, allowing very precise margin control while preserving normal tissue

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One passage describes standard use as 3 to 5 g daily after a loading phase or 3 g daily without loading, while a later passage says most evidence supports 3 to 5 g daily without a loading phase

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cDNA synthesis was performed on Gene Amp PCR thermal cycler