Additionally, autophagys capacity to degrade ferritin, contingent on the expression of NCOA4 (nuclear receptor coactivator 4), has the potential to induce ferroptosis ( Autophagy is primarily governed by LC3 proteins, specifically microtubule-associated protein 1 light chain 3 (MAP1LC3), commonly known as LC3
Yet, the etiology appears to be multifactorial, as a number of other causative factors have been suggested for KBD, including fungal toxins in grain, iodine deficiency, and contaminated drinking water (52)
Additional file 3 : Table S3
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Naunyn-Schmiedebergs Arch Pharmacol 110
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