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Jensen et al., 2018) while a low level of GLP-1R-immunoreactivity was revealed in rat hippocampus ( in vivo electrophysiological recordings showed that juxtacellular application of the active fragment of GLP-1, GLP-1 (736) amide induces an increase and then a decrease of firing activity in the hippocampal CA1 neurons

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Do not double up to "catch up." Missing a dose during the microdose phase is less disruptive than during maintenance because the sub-therapeutic doses are not producing strong effects that would be lost