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Joseph Dolence Return to Program Outline 8:00 - COMPUTATIONAL DISCOVERY OF HEARTLAND VIRUS ENDONUCLEASE INHIBITORS TARGETING MANGANESE-DEPENDENT CAP-SNATCHING ACTIVITY Kaiden Aaronson 8:15 - HIV AND ALCOHOL SYNERGIZE TO SPREAD INFLAMMATION AND CELL DEATH IN PARENCHYMAL LIVER CELLS Lukman Adepoju 8:30 - SYSTEMATIC EVALUATION OF GROWTH MEDIA AND ISOLATION METHODS INFLUENCING OUTER MEMBRANE VESICLE YIELD AND PURITY FROM ESC Sophia Kolb 8:45 - EXAMINING HOW VAPING IMPACTS THE RESPONSE OF B CELLS TO PEANUT Joseph Roeder 9:00 - PROLONGED CHANGES OF CULTURE CONDITIONS INDUCES A SHIFT IN MITOCHONDRIAL ENERGETICS OF SQUAMOUS CELL CARCINOMA CELLS Jinann Shoshara 9:15 - LINEAR QUADRATIC MODEL AND BEYOND, FOR COMBINED THERAPIES AGAINST BRAIN CANCERS Sara Strom 8:00 - COMPUTATIONAL DISCOVERY OF HEARTLAND VIRUS ENDONUCLEASE INHIBITORS TARGETING MANGANESE-DEPENDENT CAP-SNATCHING ACTIVITY Kaiden Aaronson Nebraska Wesleyan University Heartland virus (HRTV) is an emerging tick-borne pathogen associated with severe febrile illness, thrombocytopenia, and leukopenia

431 Cellular senescence is associated with a range of non-proliferative conditions, including lung fibrosis, kidney diseases, liver steatosis, metabolic syndrome related to obesity, type I and II diabetes, atherosclerosis, and neurodegenerative diseases such as Alzheimers and Parkinsons disease

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Moreover, berberine can also improve FAO and rescue mitochondrial function by inducing CPT1 and CPT2 in podocytes, which further attenuates lipid accumulation and ROS overproduction in DKD (Qin et al., 2020)

The Ontario Drug Benefit Formulary/Comparative Drug Index lists Ozempic as a Limited Use product with criteria tied to Type 2 diabetes, not weight loss alone. Full Guide for Everything you need to know about Ozempic for Weight loss Saxenda vs Ozempic Dosage and How to Use Them Saxenda is injected once daily and adjusted weekly, starting at 0.6mg daily and increasing to a 3.0mg daily maintenance dose