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Post-treatment, the cells were washed with 1X phosphate-buffered saline and stained with 15 M DCFDA-H2 or 5 M MitoSOX for 15 min at 37 C

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The risk of muscle loss is particularly pronounced in certain populations: older adults (age 65+) who already face age-related sarcopenia, sedentary individuals without resistance training stimulus for muscle preservation, and patients losing weight very rapidly

a Phase III study compared the two products in RA not sufficiently controlled by methotrexate in order to establish equivalent efficacy and comparable pharmacokinetic, safety and immunogenicity profiles

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Cell 79 , 43-53.e44