Baric I, Zschocke J, Christensen E, Duran M, Goodman SI, Leonard JV, Muller E, Morton DH, Superti-Furga A, Hoffmann GF: Diagnosis and management of glutaric aciduria type I
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(2012), is characterized by iron-dependent accumulation of lipid peroxides, distinguishing it from classical cell death modalities such as apoptosis, necrosis, and autophagy, ferroptosis exhibits a stronger dependence on intracellular iron than other regulated cell death pathways
Beutler, E., Blood , 14 , 103 (1959)
Chronotherapeutic effects of Allu on hyperphagic obesity Impaired diurnal feeding rhythm is implicated in development of obesity, diabetes, and metabolic syndrome in humans and rodents 3,4,28
For example, a patient with known heart disease might be a strong candidate for semaglutide, given that its brand name Ozempic has a specific FDA indication for reducing the risk of major cardiovascular events in people with type 2 diabetes