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52 In a large meta-analysis by Chiang et al involving 106,395 participants and 55 RCTs, GLP-1 RA therapy was associated with an increased risk of gastroesophageal reflux disease (GERD) compared to placebo, with a reported relative risk of 2.19 (95% CI: 1.483.25)
doi: 10.1017/S0007114520003207 69 SolimanMYIdrisOAFMomtazMKortamMAMAELSalehHAet al
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