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Semaglutide use and weight loss Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist that Three brand names for semaglutide have been approved by the Food and Drug Administration (FDA) for different purposes: Wegovy: FDA-approved for weight loss and reducing the risk of cardiovascular disease

doi: 10.3390/ijms160920195 100 TokiSNewcombDCPrintzRLCahillKNBoydKLNiswenderKDet al

Furthermore, reporting bias is a significant concern, potentially skewing the perception of drug safety by overemphasizing widely publicized or severe events

Larson H et al

In a highdose semaglutide trial (7.2 mg weekly), participants lost about 20.7% of body weight in 72 weeks, with a substantial portion achieving up to 25% weight loss

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