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Hum Mol Genet

Certain individuals are more likely to develop B12 deficiency, including those with: Pernicious anemia Gastrointestinal conditions (such as Crohns disease or celiac disease) A history of gastrointestinal surgery Difficulty absorbing nutrients due to age or other medical conditions For these patients, vitamin B12 injections are an effective option because they deliver the nutrient directly into the bloodstream, bypassing the digestive system and ensuring optimal absorption

[28] Pregnant and breastfeeding women are generally advised not to use Lipo-B injections as well (see above discussion in Pregnancy section)

K-means clustering was performed on the genera relative abundance data using the R script in the Supplementary Materials Scripts .zip file (KMScript), and clusters were plotted