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Hydrophobic residues in p53 TAD2 are critical for interaction with FOXO4 FHD Based on the significance of both the TAD2 region and the C-terminus of p53 in interacting with the FOXO4 FHD, we attempted to develop an inhibitor targeting the FOXO4-p53 interaction

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Pharmaceutical versions of this hormone amplify these natural effects, which makes GLP-1 medications effective tools for managing type 2 diabetes and, at higher doses, for promoting weight loss

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