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However, its close relation with PCOS, obesity, and insulin resistance was not statistically significant, which suggests that its effects could be more related to certain metabolic parameters instead of being globally beneficial in the clinical manifestation of PCOS [133]
doi: 10.3389/fendo.2022.825934 55 VeemanMTAxelrodJDMoonRT
Funding DJD is supported by a Banting and Best Diabetes Centre Chair in Incretin Biology, the Sinai Health Novo Nordisk Foundation Fund in Regulatory Peptides, and CIHR Foundation grant 154321
Reduced appearance of pigmentation over time
In fact, whether incubated with DTT or TRX-f1, the residual activity of the oxidized proteins GSAAT(C190S) and GSAAT(C168S/C190S) could scarcely be enhanced at all, which points to an impaired redox sensitivity of these mutants
