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Long-term studies

NFE2L2, Factor erythroid 2-related factor 2

improved collagen organization and tensile strength (PMID: 21030672) Gastrointestinal: Protection against NSAID-induced ulcers, IBD models, fistula healing in preclinical studies (PMID: 31158953) Nerve: Enhanced sciatic nerve regeneration

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Epitalon, also known as epithalamin or epithalon, is a synthetic tetrapeptide composed of Ala-Glu-Asp-Gly, derived from a naturally occurring pineal gland extract called epithalamin

Despite its evocative name, its precise mechanism remains incompletely understood, which is exactly what makes it an enduring subject of experimental investigation into sleep, stress and neuroprotection