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SOD1 (superoxide dismutase) GHK-Cu enhances endogenous antioxidant defenses by increasing SOD1 expression, which neutralizes superoxide radicals implicated in photoaging and oxidative DNA damage

References 1.Yildiz BO, Bozdag G, Yapici Z, Esinler I, Yarali H

Zerbinati C, Caponecchia L, Rago R, et al

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Nat.(Natural Science Edition) 27 (04), 7981

Activation of GIPR signalling attenuates cardiac hypertrophy and fibrosis in mice with experimental hypertension [125], whereas loss of cardiomyocyte GIPR signalling is cardioprotective in mice with ischaemic cardiac injury secondary to coronary artery occlusion [124]