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APOE comes in four variants: APOE1 (extremely rare and not considered further), APOE2 (rare), APOE3 (most common), and APOE4 (common) (Belloy et al., 2019)

Temporary Fatigue or Lethargy Some researchers observe a feeling of tiredness or lethargy shortly after administration

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Such dangers partially explain doctors interest in helping people avoid excessive weight