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While GHSR1a activity in the hypothalamus is likely heavily involved in homeostatic mechanisms, its presence in extra hypothalamic regions, including a number of limbic and midbrain structures like the ventral tegmental area (VTA), suggest that this receptor is associated in processes associated with learning and motivation (Abizaid et al., 2006
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doi: 10.1126/science.270.5240.1326 95 BobustucGCKassamABRovinRAJeudySSmithJSIsleyBet al
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