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Participants receiving the highest dose of tirzepatide lost an average of 22.5% of their body weight over 68 weeks, compared to 2.4% with placebo

In clinical trials, participants taking the 25 mg dose achieved an average weight loss of 13.6% over 64 weeks

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Minimize ultra-processed foods, excessive added sugars, and alcohol all of which increase oxidative and inflammatory burden on pathways that interact with muscle growth and IGF-1 LR3-related signaling

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