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The carbon fluorinated polymeric unit, that is able to physically entrap molecular O 2 , was incorporated into the polymer backbone for selective delivery of O 2 to the target tissue

106 Unlike live cell-based formulations, EVs carry no risk of replication and therefore exhibit a superior safety profile

Dose-Response 12 , 480497 (2014)

Overall discontinuation rates were similar across study arms, though discontinuations related to adverse events were higher in participants with lower baseline BMIs

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Alternatively, SGLT-2is and GLP-1RAs may correct these microbiota alterations and possibly induce improvements in metabolic profile seen in more advanced kidney disease, e.g