doi: 10.1056/NEJMoa2110956
Dozens of clinical trials are underway that explore the use of GLP-1 agonists for other conditions, such as liver disease, kidney disease, alcohol use disorders, polycystic ovary syndrome, sleep apnea, and Alzheimers
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Experimental studies have shown that GLP-1 RAs can reverse early retinal changes associated with DR, restoring blood-retinal barrier integrity and preventing retinal cell death
Gastrointestinal side effectsnausea, constipation, and reduced appetiteare common with GLP-1 use and occur independently of immune function
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