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Wegovy (semaglutide 2.4 mg) is a prescription medicine licensed in the UK for weight management in adults with obesity (BMI 30 kg/m) or overweight (BMI 27 kg/m) with at least one weight-related comorbidity, such as type 2 diabetes, hypertension, or obstructive sleep apnoea
Importantly, those effects were observed only in animal and in-vitro models , not in verified human clinical settings
This is why preserving muscle mass during weight loss is an important clinical consideration for anyone undertaking significant weight reduction, including those using GLP-1 medications
B.FarhamF.KhorramA.SheshboloukiS.ZokaeiM.et al (2023)
NCT05316701)
Effects of the Fatty Acid Amide Hydrolase (FAAH) Inhibitor URB597 on Pain-Stimulated and Pain-Depressed Behavior in Rats
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