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Current statistics suggest that India, China, United States, Russia, Brazil, and South Africa are the world leaders in per capita consumption of antibiotics (Van Boeckel et al., 2014)

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The extended half-life of approximately 7 days is due to albumin binding and resistance to DPP-4 degradation, enabling convenient once-weekly dosing [1]

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"Pathophysiology of colonic causes of chronic constipation"